diff --git a/.env.example b/.env.example
index a1ea58cc7..364b7e3e0 100644
--- a/.env.example
+++ b/.env.example
@@ -26,6 +26,8 @@ COMPANION_AWS_REGION="AWS REGION"
 COMPANION_AWS_PREFIX="OPTIONAL PREFIX"
 # to enable S3 Transfer Acceleration (default: false)
 # COMPANION_AWS_USE_ACCELERATE_ENDPOINT="false"
+# to enable S3 path style uploads (default: false), this is useful for localstack support
+# COMPANION_AWS_FORCE_PATH_STYLE="true"
 # to set X-Amz-Expires query param in presigned urls (in seconds, default: 800)
 # COMPANION_AWS_EXPIRES="800"
 # to set a canned ACL for uploaded objects: https://docs.aws.amazon.com/AmazonS3/latest/dev/acl-overview.html#canned-acl
diff --git a/docs/companion.md b/docs/companion.md
index c27063a17..f06292761 100644
--- a/docs/companion.md
+++ b/docs/companion.md
@@ -501,6 +501,12 @@ the following arguments:
 - metadata provided by the user for the file (will be `undefined` for local
   uploads)
 
+#### `s3.forcePathStyle` `COMPANION_AWS_FORCE_PATH_STYLE`
+
+This adds support for setting the S3 client’s `forcePathStyle` option. That is
+necessary to use Uppy/Companion alongside localstack in development
+environments. **Default**: `false`.
+
 ##### `s3.region` `COMPANION_AWS_REGION`
 
 The datacenter region where the target bucket is located.
diff --git a/examples/aws-companion/server.cjs b/examples/aws-companion/server.cjs
index 98dc31231..cf2b84357 100644
--- a/examples/aws-companion/server.cjs
+++ b/examples/aws-companion/server.cjs
@@ -35,6 +35,7 @@ const options = {
     bucket: process.env.COMPANION_AWS_BUCKET,
     region: process.env.COMPANION_AWS_REGION,
     endpoint: process.env.COMPANION_AWS_ENDPOINT,
+    forcePathStyle: process.env.COMPANION_AWS_FORCE_PATH_STYLE === 'true',
   },
   server: { host: 'localhost:3020' },
   filePath: DATA_DIR,
diff --git a/examples/aws-nodejs/index.js b/examples/aws-nodejs/index.js
index c067565d5..cb8c42cb1 100644
--- a/examples/aws-nodejs/index.js
+++ b/examples/aws-nodejs/index.js
@@ -61,6 +61,7 @@ function getS3Client () {
       accessKeyId: process.env.COMPANION_AWS_KEY,
       secretAccessKey: process.env.COMPANION_AWS_SECRET,
     },
+    forcePathStyle: process.env.COMPANION_AWS_FORCE_PATH_STYLE === 'true',
   })
   return s3Client
 }
diff --git a/examples/digitalocean-spaces/server.cjs b/examples/digitalocean-spaces/server.cjs
index dc369fa8b..e6d10ce97 100644
--- a/examples/digitalocean-spaces/server.cjs
+++ b/examples/digitalocean-spaces/server.cjs
@@ -14,6 +14,7 @@ const companion = require('../../packages/@uppy/companion')
  *   - COMPANION_AWS_KEY - Your access key ID
  *   - COMPANION_AWS_SECRET - Your secret access key
  *   - COMPANION_AWS_BUCKET - Your space's name.
+ *   - COMPANION_AWS_FORCE_PATH_STYLE - Indicates if s3ForcePathStyle should be used rather than subdomain for S3 buckets.
  */
 
 if (!process.env.COMPANION_AWS_REGION) throw new Error('Missing Space region, please set the COMPANION_AWS_REGION environment variable (eg. "COMPANION_AWS_REGION=ams3")')
@@ -43,6 +44,7 @@ const { app: companionApp } = companion.app({
     secret: process.env.COMPANION_AWS_SECRET,
     bucket: process.env.COMPANION_AWS_BUCKET,
     region: process.env.COMPANION_AWS_REGION,
+    forcePathStyle: process.env.COMPANION_AWS_FORCE_PATH_STYLE === 'true',
   },
   server: { host },
   filePath: DATA_DIR,
diff --git a/packages/@uppy/companion/env_example b/packages/@uppy/companion/env_example
index 89e7b2298..08b3e0acf 100644
--- a/packages/@uppy/companion/env_example
+++ b/packages/@uppy/companion/env_example
@@ -39,6 +39,7 @@ COMPANION_AWS_BUCKET=
 COMPANION_AWS_ENDPOINT=
 COMPANION_AWS_REGION=
 COMPANION_AWS_PREFIX=
+COMPANION_AWS_FORCE_PATH_STYLE="false"
 
 COMPANION_ZOOM_KEY=
 COMPANION_ZOOM_SECRET=
diff --git a/packages/@uppy/companion/src/server/s3-client.js b/packages/@uppy/companion/src/server/s3-client.js
index d5b5c48be..74717d238 100644
--- a/packages/@uppy/companion/src/server/s3-client.js
+++ b/packages/@uppy/companion/src/server/s3-client.js
@@ -29,6 +29,7 @@ module.exports = (companionOptions, createPresignedPostMode = false) => {
     /** @type {import('@aws-sdk/client-s3').S3ClientConfig} */
     let s3ClientOptions = {
       region: s3.region,
+      forcePathStyle: Boolean(s3.forcePathStyle)
     }
 
     if (s3.useAccelerateEndpoint) {
diff --git a/packages/@uppy/companion/src/standalone/helper.js b/packages/@uppy/companion/src/standalone/helper.js
index dbc3ab875..347dec9cd 100644
--- a/packages/@uppy/companion/src/standalone/helper.js
+++ b/packages/@uppy/companion/src/standalone/helper.js
@@ -133,6 +133,7 @@ const getConfigFromEnv = () => {
       process.env.COMPANION_AWS_USE_ACCELERATE_ENDPOINT === 'true',
       expires: parseInt(process.env.COMPANION_AWS_EXPIRES || '800', 10),
       acl: process.env.COMPANION_AWS_ACL,
+      forcePathStyle: process.env.COMPANION_AWS_FORCE_PATH_STYLE === 'true',
     },
     server: {
       host: process.env.COMPANION_DOMAIN,